Newsletters - October - November 2004

An independent review conducted by CANTOX Health Sciences International confirmed the safety of Sabinsa's ForsLean ® ( Coleus forskohlii extract), ingredient for use in dietary supplements. Coleus forskohlii is the only known plant source of forskolin, a natural compound that has been shown to increase lean body mass and help optimize body composition through the activation of cAMP. US Patent #5,804,596 (international patents pending) held by Sabinsa Corporation describes the use of forskolin as a weight management ingredient and in the management of mood disorders.

A letter issued by CANTOX states "the available information supports the safety of ForsLean ® at the intake level of 500 mg per day resulting in a dose of 50 mg of forskolin." CANTOX findings were based on scientific information and data, provided by Sabinsa Corporation and obtained from thirdparty literature, pertaining to the safety of ForsLean.

In the conclusion of its review, CANTOX states "if serious side effects or adverse events had been suspected to be linked to forskolin, one might expect reports of adverse effects in literature." CANTOX notes that there have been no Adverse Effect Reports filed in association with forskolin. Additionally, C A N T O X asserts "clinical studies in which ForsLean® was administered at doses of up to 500 mg/day for periods of up to 12 weeks have demonstrated no significant effects on clinical chemistry or hematological parameters, nor any significant detrimental effects on blood pressure and thyroid function."

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